Frequently asked questions
Here are some quick answers to commonly asked questions. If you have questions about ODOMZO® (sonidegib), be sure to discuss them with your doctor.
Q: How do I take ODOMZO?
A: Take ODOMZO exactly as your doctor tells you. Take ODOMZO one time each day.
Q: Can I take ODOMZO with food?
A: ODOMZO must be taken on an empty stomach. Take ODOMZO at least 1 hour before or 2 hours after a meal.
Q: What if I forget to take my pill?
A: If you miss a dose, skip the missed dose. Take your next dose as scheduled. Do not take 2 doses to make up for a missed dose.
Q: How long should I take ODOMZO?
A: Take ODOMZO for as long as your doctor tells you. He or she will recommend that you continue taking ODOMZO as long as it's working for you and your side effects are tolerable. In a clinical study, the median duration of response with ODOMZO was 26.1 months. That means that half of patients who responded to ODOMZO saw improvement for less than 26.1 months, while the other half saw improvement for more than 26.1 months.
Q: Are there any drug interactions with ODOMZO?
A: There are interactions with ODOMZO and certain medicines. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Q: What are the most serious side effects?
A: ODOMZO can cause your baby to die before it is born (be stillborn) or cause your baby to have severe birth defects. Muscle spasms and muscle pain are common with ODOMZO, but can also sometimes be symptoms of serious muscle problems. ODOMZO can increase your risk of muscle pain and, rarely, a serious condition caused by injury to the muscles (rhabdomyolysis) that can lead to kidney damage.
Q: What are the most common side effects?
A: The most common side effects for ODOMZO include muscle spasms and pain, hair loss, change in taste, tiredness, nausea, diarrhea, weight loss, decreased appetite, stomach area (abdominal) pain, headache, vomiting, and itching.
Q: What if I can’t tolerate the side effects?
A: Discuss any side effects with your doctor. Let your doctor know right away if you experience side effects that bother you or do not go away.
Q: Can I father a child while taking ODOMZO?
A: Males must not father a child or donate semen while taking ODOMZO and for 8 months after stopping treatment.
Q: Can I get help with my co-pays for ODOMZO?
A: You may be eligible for immediate co-pay savings on your next prescription. To find out, call 1-877-636-6961 or visit us at www.activatethecard.com/7436.
Q: What should I avoid while taking ODOMZO?
A: Do not donate blood or blood products while you are taking ODOMZO and for 20 months after your final dose. Do not donate semen while taking ODOMZO and for at least 8 months after your final dose. ODOMZO can cause absence of menstrual periods (amenorrhea) in females who are able to become pregnant. It is not known if amenorrhea is permanent. Talk to your healthcare provider if you have concerns about fertility.